Pieri Lab

We are housed at the Department of Life and Health Sciences, Human Biology Program, of the University of Nicosia, Cyprus

Research

We study digestion and nutrient transport through the gastrointestinal tract in physiological and pathophysiological conditions using cell culture and animal models focusing on peptides and microRNAs. We are also interested in inherited kidney diseases and the molecular mechanisms behind Collagen IV inherited nephropathies. Finally, we investigate the contribution of individual patient genotype and biomarkers (microRNAs) in the treatment of various pathologies

MICROFOOD

Bovine XenomiRs as a novel potential mechanism for Colorectal Cancer (CRC) initiation and progression

Aphasia Rehabilitation (ASPIRE)

Investigating the efficacy of TMS in aphasia rehabilitation.

SUSTAIN

School pupils work for sustainable landscapes

Myrtani Pieri

Assistant Professor of Human Anatomy and Physiology

University of Nicosia

Principal Investigator

Head of the Pieri Lab at the Department of Life and Health Sciences, University of Nicosia, based in Nicosia, Cyprus. My lab’s research is focused on gastrointestinal physiology and nutrient transport in various physiological and pathophysiological conditions. We are also interested in inherited kidney disorders and the role of the Unfolded Protein Response (UPR) in human pathology. We have incorporated a repertoire of in vitro and in vivo models to address our research questions. Cell culture, migration, proliferation, wound healing assays, in vitro digestion models, animal models of disease and more. We are also interested in Science outreach and Education related to Human Anatomy and Physiology.

Interests

Nutrient transport
microRNAs
Unfolded Protein Response Pathway (UPR)
Collagen IV Nephropathies

Education

PhD in Human Anatomy and Physiology, 2007
University of Oxford, UK
BA in Biology, 2003
University of Patras, Greece

People

Research Assistants

Elena Theori

Lab Assistant

Bovine microRNAs, Colorectal cancer, Human Digestion

Students

Erato Christofidou

Student

Science literacy, Biology education

George Iliadis

Student

Ingested microRNAs, Inter-species interaction, Microbiome

Collaborators

Constantinos Deltas

Professor, Director, Molecular Medicine Research Center

Human molecular genetics, Molecular and cellular mechanisms of disease development, Inherited kidney diseases, Biobanking

Kyriacos Felekkis

Associate Professor, Head of Department of Life and Health Sciences

microRNAs, Cancer, Biomarkers

Maria Kambanaros

Associate Professor of Speech Pathology

Language impairments in multilingual individuals, Aphasia, Transcranial Magnetic Stimulation

Nikos Konstantinou

Assistant Professor of Cognitive Neuroscience

Attention, Working Memory, Perception, Neuroimaging (MRI), Brain Stimulation (TMS/tDCS)

Science Communication

How deep do you think the love of a mother for her child is?

Watch Myrtani’s FameLab International presentation at Cheltenham Science Festival 2011

Sep 14, 2019 6:04 PM

Magical Science

Watch Myrtani’s talk at TEDx Nicosia 2012

Sep 14, 2019 6:04 PM

Publications

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Thiodipeptides targeting the intestinal oligopeptide transporter as a general approach to improving oral drug delivery

The broad substrate capacity of the intestinal oligopeptide transporter, PepT1, has made it a key target of research into drug …

Foley David W, Pathak Ravindra B, Phillips Theresa R, Wilson Gayle L, Bailey Patrick D, Pieri Myrtani, Senan Anish, Meredith David

A functional variant in NEPH3 gene confers high risk of renal failure in primary hematuric glomerulopathies. Evidence for predisposition to microalbuminuria in the general population

Background Recent data emphasize that thin basement membrane nephropathy (TBMN) should not be viewed as a form of benign familial …

Voskarides Konstantinos, Stefanou Charalambos, Pieri Myrtani, Demosthenous Panayiota, Felekkis Kyriakos, Arsali Maria, Athanasiou Yiannis, Xydakis Dimitris, Stylianou Kostas, Daphnis Eugenios, and others

Co-Inheritance of Functional Podocin Variants with Heterozygous Collagen IV Mutations Predisposes to Renal Failure

Background/Aims: A subset of patients who present with proteinuria and are diagnosed with focal segmental glomer- ulosclerosis (FSGS) …

Stefanou Charalambos, Pieri Myrtani, Savva Isavella, Georgiou Georgia, Pierides Alkis, Voskarides Konstantinos, Deltas Constantinos

Frequency of COL4A3/COL4A4 Mutations amongst Families Segregating Glomerular Microscopic Hematuria and Evidence for Activation of the Unfolded Protein Response. Focal and Segmental Glomerulosclerosis Is a Frequent Development during Ageing

Familial glomerular hematuria(s) comprise a genetically heterogeneous group of conditions which include Alport Syndrome (AS) and thin …

Papazachariou Louiza, Demosthenous Panayiota, Pieri Myrtani, Papagregoriou Gregory, Savva Isavella, Stavrou Christoforos, Zavros Michael, Athanasiou Yiannis, Ioannou Kyriakos, Patsias Charalambos, and others

Evidence for Activation of the Unfolded Protein Response in Collagen IV Nephropathies

Thin-basement-membrane nephropathy (TBMN) and Alport syndrome (AS) are progressive collagen IV nephropathies caused by mutations in …

Pieri Myrtani, Stefanou Charalambos, Zaravinos Apostolos, Erguler Kamil, Stylianou Kostas, Lapathitis George, Karaiskos Christos, Savva Isavella, Paraskeva Revekka, Dweep Harsh, and others

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